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Bioinformatics Advance Access originally published online on April 15, 2004
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Bioinformatics 20(9) © Oxford University Press 2004; all rights reserved.

PINdb: a database of nuclear protein complexes from human and yeast

Phuong-Van Luc and Paul Tempst *

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA

Received on July 18, 2003; revised on November 18, 2003; accepted on November 25, 2003
Advance Access Publication April 15, 2004

Summary: Proteins Interacting in the Nucleus database (PINdb) is a database of protein complexes purified from the nucleus of human and yeast cells. It is compiled from the published literature and existing databases. Currently, PINdb contains mostly protein complexes that may be involved in gene transcription. To facilitate comparative analyses and identification of protein complexes, the compositional information is integrated with standardized gene nomenclature, annotation and protein sequences from public databases. The PINdb web interface provides a number of tools for (1) comparison of protein complexes, (2) search for a protein complex by its published name or by a partial list of its components and (3) browsing specific subsets or a functional classification of the complexes.

Availablity: http://pin.mskcc.org

Contact: p-tempst{at}mskcc.org

* To whom correspondence should be addressed.


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