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Bioinformatics Advance Access published online on February 26, 2004
Bioinformatics, doi:10.1093/bioinformatics/bth156
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received October 6, 2003
Revised January 19, 2004
Accepted January 28, 2004

Applications note

FunMap: functional mapping of complex traits

Chang-Xing Ma 1, Rongling Wu 1*, George Casella 1

1 Department of Statistics, University of Florida, Gainesville, FL 326111, USA

* To whom correspondence should be addressed. E-mail: rwu{at}stat.ufl.edu.


  Abstract

Summary: FunMap is a web-based user interface designed to map quantitative trait loci (QTL) affecting function-valued traits or infinite-dimensional traits in well-structured pedigrees or natural populations. User input includes three files: longitudinal trait data, marker genotypes and/or a linkage map. This software allows for a systematic genome-wide scan and significance test of QTL throughout the map. The dynamic change of QTL effects during the time course of growth is automatically drawn, from which specific biological hypotheses regarding the genetic control mechanisms of growth and development can be tested.

Availability: http://web.biostat.ufl.edu/~cma/genetics/software.html


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